Phenotype Image Detail

Image

Caption

A substitution mutation in Dil1 leads to situs inversus and posterior truncation in Dll1^m594592Hubr/Dll1^m594592Hubr (Dll1^E26G) embryos. (D-I) H&E stainings on transverse sections at E9.5. The asterisk in E marks reversed looping compared to wild-type (D). NT, neural tube; Ht, heart. The arrow in G indicates an ectopic neural tube (F). Irregularly shaped neural tube (asterisks) and somites (arrows) in mutants (H,I). Som, somites; Nc, notochord.

Copyright

This image is from Wansleeben C, PLoS One 2011;6(4):e19357, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:173681

Associated Alleles

Symbol	Name
Dll1^m594592Hubr	delta like canonical Notch ligand 1; mutation 594592, Hubrecht Institute

Associated Genotypes

Allelic Composition	Genetic Background
Dll1^m594592Hubr/Dll1^m594592Hubr	involves: C57BL/6 * FVB/N