Phenotype Image Detail

Image

Caption

Agr2^tm1.2Erle/Agr2^tm1.2Erle mice are devoid of intestinal mucus. (A and B) Immunohistochemical detection of AGR2 protein in small intestine (A) and colon (B) of wild-type (Agr2+/+) and mutant (Agr2-/-) mice. (C and D) Periodic acid-Schiff staining of glycoproteins in small intestine (C) and colon (D). (E and F) Immunohistochemical detection of MUC2 protein in small intestine (E) and colon (F). (Scale bar: 50 um.)

Copyright

This image is from Park SW, Proc Natl Acad Sci U S A 2009 Apr 28;106(17):6950-5. Copyright 2009 National Academy of Sciences, U.S.A. J:148339

Associated Alleles

Symbol	Name
Agr2^tm1.2Erle	anterior gradient 2; targeted mutation 1.2, David J Erle

Associated Genotypes

Allelic Composition	Genetic Background
Agr2^tm1.2Erle/Agr2^tm1.2Erle	involves: 129S4/SvJae * FVB/N