Reference
Figure
ID
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J:281311
Nakano Y, et al., Cell Rep. 2019 Apr 16;27(3):860-871.e8
S4
MGI:7540992
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Image |
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Caption | (C,D) RT-PCR analysis of alternative splicing of the indicated exons of wild-type (WT) and dMut (Srrm3gt/gt;Srrm4bv/bv) on E19. The RT-PCR primers were designed from the constitutive exons (white boxes) flanking the tested alternative exons (red boxes). Purple boxes indicate alternative exons whose SRRM3-SRRM4-dependent regulation is revealed by RT-PCR but was not detected by MJAY analysis. Black boxes indicate alternative exons not regulated by SRRM3-SRRM4. Thin rectangles indicate UTRs. Asterisks indicate splice forms that are predicted to be the subject of nonsense-mediated mRNA decay (NMD). Exon (ex) numbers are shown if more than one exon in the same transcript is regulated by SRRM3-SRRM4. Arrowheads indicate two sets of primer pairs used for the analysis of Atl2 splicing (C). on E19. Asterisk indicates a Cacnb4 splice form that is predicted to be the subject of NMD (D). Abbreviation: nonsense-mediated mRNA decay (NMD) |
Copyright | This image is from Nakano Y, Cell Rep 2019 Apr 16;27(3):860-871.e8, and is displayed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |
Associated Assays |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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