Phenotype Image Detail

Image

Caption

Cherp^em1(IMPC)J/Cherp^em1(IMPC)J embryos cannot be recovered at E7.5 (0/32), however there are excess resorption sites suggesting mutants elicit a decidual response in vivo. Homozygous mutants are recovered at expected ratios at E3.5 and appear as irregular morula or early blastocysts. Mutants hatch from the zona pellucida and form outgrowths with no defined inner cell mass and few trophectoderm cells. RNA-seq data indicates robust zygotic and 8-cell expression. Additional information at websites.umass.edu/jmager/Cherp

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated
Alleles

Symbol	Name
Cherp^em1(IMPC)J	calcium homeostasis endoplasmic reticulum protein; endonuclease-mediated mutation 1, Jackson

Associated
Genotypes

Allelic Composition	Genetic Background
Cherp^em1(IMPC)J/Cherp^em1(IMPC)J	C57BL/6NJ-Cherp^em1(IMPC)J/Mmjax

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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