Phenotype Image Detail

Image

Caption

Ccdc93^em1(IMPC)J/Ccdc93^em1(IMPC)J embryos are recovered at expected Mendelian ratios at E7.5 but are much smaller than littermates. Mutants show consistent phenotype including severe developmental delay, poorly organized extraembryonic tissues, no Brachyury (T)-positive cells, and active-Trp53-positive cells indicating cell death. RNA-seq data indicates robust maternal and post-2-cell expression. Additional information at websites.umass.edu/jmager/Ccdc93

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Ccdc93^em1(IMPC)J	coiled-coil domain containing 93; endonuclease-mediated mutation 1, Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Ccdc93^em1(IMPC)J/Ccdc93^em1(IMPC)J	C57BL/6NJ-Ccdc93^em1(IMPC)J/Mmjax