Phenotype Image Detail

Image

Caption

Dhx8^em1(IMPC)Mbp/Dhx8^em1(IMPC)Mbp embryos cannot be recovered at E7.5 (0/33), nor are there excess resorption sites. Homozygous mutants are recovered at E3.5 and appear as early blastocysts. Mutants hatch from the zona and form irregular outgrowths with poorly defined inner cell mass colony when cultured in vitro. RNA-seq data indicates robust maternal and post-zygotic expression. Additional information at websites.umass.edu/jmager/Dhx8

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Dhx8^em1(IMPC)Mbp	DEAH-box helicase 8; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis

Associated Genotypes

Allelic Composition	Genetic Background
Dhx8^em1(IMPC)Mbp/Dhx8^em1(IMPC)Mbp	C57BL/6NCrl-Dhx8^em1(IMPC)Mbp/Mmucd