Phenotype Image Detail

Image

Caption

Hars2^em1(IMPC)J/Hars2^em1(IMPC)J mutants can be recovered at E7.5 but are much smaller than littermates. A rudimentary egg-cyclinder has formed, but no morphological primitive streak or other hallmarks typical of gastrulation at E7.5 (i.e. node, headfolds) are present. RNA-seq data indicates robust maternal and post-zygotic expression. Additional information at websites.umass.edu/jmager/Hars2

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Hars2^em1(IMPC)J	histidyl-tRNA synthetase 2; endonuclease-mediated mutation 1, Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Hars2^em1(IMPC)J/Hars2^em1(IMPC)J	C57BL/6NJ-Hars2^em1(IMPC)J/Mmjax