Phenotype Image Detail

Image

Caption

Ipo7^em1(IMPC)Mbp/Ipo7^em1(IMPC)Mbp embryos cannot be recovered at E7.5 (0/22), nor are there excess resorption sites. Homozygous mutants are recovered at expected ratios at E3.5 and appear as abnormal blastocysts. Mutants do hatch from the zona and form outgrowths in vitro. RNA-seq data indicates robust post-zygotic expression. Additional information at websites.umass.edu/jmager/Ipo7

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Ipo7^em1(IMPC)Mbp	importin 7; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis

Associated Genotypes

Allelic Composition	Genetic Background
Ipo7^em1(IMPC)Mbp/Ipo7^em1(IMPC)Mbp	C57BL/6NCrl-Ipo7^em1(IMPC)Mbp/Mmucd