Phenotype Image Detail

Image

Caption

Dnaaf2^{tm1.1(KOMP)Vlcg}/Dnaaf2^{tm1.1(KOMP)Vlcg} mutants are recovered in expected ratios at E7.5 but are smaller than littermates. By E8.5 embryos have stalled in development. Gastrulation has occurred with A-P specification, but there are left-right defects along with pleiotropic defects (see Cheong et al 2019). RT-PCR indicates robust expression postimplantation. Knock-in LacZ reporter expression is node specific at E7.5 and E8.5. Additional information at websites.umass.edu/jmager/Dnaaf2

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Dnaaf2^tm1.1(KOMP)Vlcg	dynein, axonemal assembly factor 2; targeted mutation 1.1, Velocigene

Associated Genotypes

Allelic Composition	Genetic Background
Dnaaf2^tm1.1(KOMP)Vlcg/Dnaaf2^tm1.1(KOMP)Vlcg	B6N(Cg)-Dnaaf2^tm1.1(KOMP)Vlcg/J