Phenotype Image Detail

Image

Caption

Atp2b1^{tm1b(KOMP)Wtsi}/Atp2b1^{tm1b(KOMP)Wtsi} embryos cannot be recovered at E7.5 (0/38), nor are there excess resorption sites. Homozygous mutants are recovered at expected ratios at E3.5 and appear as early blastocysts. Mutants hatch from the zona and form outgrowths with apparent inner cell mass but limited/no trophectoderm or primitive endoderm cells. RT-PCR indicates robust maternal and post-implantation expression. Additional information at websites.umass.edu/jmager/Atp2b1

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Atp2b1^tm1b(KOMP)Wtsi	ATPase, Ca++ transporting, plasma membrane 1; targeted mutation 1b, Wellcome Trust Sanger Institute

Associated Genotypes

Allelic Composition	Genetic Background
Atp2b1^tm1b(KOMP)Wtsi/Atp2b1^tm1b(KOMP)Wtsi	C57BL/6N-Atp2b1^tm1b(KOMP)Wtsi/Tcp