Phenotype Image Detail

Image

Caption

Elof1^{tm1.1(KOMP)Vlcg}/Elof1^{tm1.1(KOMP)Vlcg} mutants are recovered in expected ratios at E7.5 but appear smaller than littermates. No molecular or morphological evidence of the primitive streak are evident, nor are the node or other hallmarks typical of E7.5 (i.e. headfolds) present. Both LacZ reporter and RT-PCR indicate wide-spread expression with notable absence in the visceral endoderm. See Tellier et al 2019 for more detail and in depth analysis. Additional information at websites.umass.edu/jmager/Elof1

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Elof1^tm1.1(KOMP)Vlcg	ELF1 homolog, elongation factor 1; targeted mutation 1.1, Velocigene

Associated Genotypes

Allelic Composition	Genetic Background
Elof1^tm1.1(KOMP)Vlcg/Elof1^tm1.1(KOMP)Vlcg	B6N(Cg)-Elof1^tm1.1(KOMP)Vlcg/J