Phenotype Image Detail

Image

Caption

Washc4^em1(IMPC)J/Washc4^em1(IMPC)J mutants are recovered in expected ratios at E7.5 but are much smaller than littermates. A rudimentary egg-cylinder has formed, but no morphological primitive streak or other hallmarks typical of gastrulation at E7.5 (i.e. node, headfolds) are present. RT-PCR indicates robust maternal expression and expression in gastrulation stages, except at E8.5. Additional information at websites.umass.edu/jmager/Washc4

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Washc4^em1(IMPC)J	WASH complex subunit 4; endonuclease-mediated mutation 1, Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Washc4^em1(IMPC)J/Washc4^em1(IMPC)J	C57BL/6NJ-Washc4^em1(IMPC)J/Mmjax