Phenotype Image Detail

Image

Caption

Riok1^em1(IMPC)J/Riok1^em1(IMPC)J embryos cannot be recovered at E7.5 (0/29), nor are there excess resorption sites. Homozygous mutants are recovered at expected ratios at E3.5 and appear as normal blastocysts. Mutants hatch from the zona and form normal outgrowths with apparent inner cell mass, trophectoderm and primitive endoderm cells. RT-PCR indicates robust maternal and post-implantation expression. Additional information at websites.umass.edu/jmager/Riok1

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Riok1^em1(IMPC)J	RIO kinase 1; endonuclease-mediated mutation 1, Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Riok1^em1(IMPC)J/Riok1^em1(IMPC)J	C57BL/6NJ-Riok1^em1(IMPC)J/Mmjax