Phenotype Image Detail

Image

Caption

Orc2^em1(IMPC)J/Orc2^em1(IMPC)J embryos cannot be recovered at E7.5 (0/26), however there are excess resorption sites suggesting mutants elicit a decidual response in vivo. Homozygous mutants are recovered at E3.5 and appear as blastocysts. Mutants hatch from the zona and form in vitro outgrowths. RNA-seq data indicates robust expression at all stages examined. Additional information at websites.umass.edu/jmager/Orc2

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Orc2^em1(IMPC)J	origin recognition complex, subunit 2; endonuclease-mediated mutation 1, Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Orc2^em1(IMPC)J/Orc2^em1(IMPC)J	C57BL/6NJ-Orc2^em1(IMPC)J/Mmjax