Phenotype Image Detail

Image

Caption

Pop5^em1(IMPC)J/Pop5^em1(IMPC)J embryos cannot be recovered at E7.5 (0/23), nor are there excess resorption sites. Homozygous mutants are recovered at expected ratios at E3.5 and appear as uncompacted morula. Mutants fail to hatch from the zona and are dead after 72 hr in vitro, never forming blastocysts. RNA-seq data indicates robust maternal and post-8-cell expression. Additional information at websites.umass.edu/jmager/Pop5

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Pop5^em1(IMPC)J	processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae); endonuclease-mediated mutation 1, Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Pop5^em1(IMPC)J/Pop5^em1(IMPC)J	C57BL/6NJ-Pop5^em1(IMPC)J/Mmjax