Phenotype Image Detail

Image

Caption

Tbcc^em1(IMPC)J/Tbcc^em1(IMPC)J embryos cannot be recovered at E7.5 (0/25), however excess resorption sites suggest mutants elicit a decidual response in vivo. Homozygous mutants are recovered at expected ratios at E3.5 and are blastocysts. Mutants hatch from the zona and form outgrowths with apparent trophectoderm cells but limited/no inner cell mass. RNA-seq data indicates robust maternal and post-zygotic expression. Additional information at websites.umass.edu/jmager/Tbcc

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Tbcc^em1(IMPC)J	tubulin-specific chaperone C; endonuclease-mediated mutation 1, Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Tbcc^em1(IMPC)J/Tbcc^em1(IMPC)J	C57BL/6NJ-Tbcc^em1(IMPC)J/Mmjax