Phenotype Image Detail

Image

Caption

Tsen54^em1(IMPC)J/Tsen54^em1(IMPC)J embryos cannot be recovered at E7.5 (0/32), however there are excess resorption sites suggesting mutants elicit a decidual response in vivo. Homozygous mutants are recovered at expected ratios at E3.5 and appear as morula. Mutants fail to hatch from the zona and are dead after 72 hr in vitro outgrowth culture. RNA-seq data indicates robust maternal and embryonic expression. Additional information at websites.umass.edu/jmager/Tsen54

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Tsen54^em1(IMPC)J	tRNA splicing endonuclease subunit 54; endonuclease-mediated mutation 1, Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Tsen54^em1(IMPC)J/Tsen54^em1(IMPC)J	C57BL/6NJ-Tsen54^em1(IMPC)J/Mmjax