Phenotype Image Detail

Image

Caption

Nifk^em1(IMPC)Mbp/Nifk^em1(IMPC)Mbp embryos cannot be recovered at E7.5 (0/30), nor are there excess resorption sites. Homozygous mutants are recovered at E3.5 and appear as dying morula. Mutants fail to hatch from the zona and are dead after 72hr in vitro, never forming outgrowths. RNA-seq data indicates robust post-zygotic expression. Additional information at websites.umass.edu/jmager/Nifk

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Nifk^em1(IMPC)Mbp	nucleolar protein interacting with the FHA domain of MKI67; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis

Associated Genotypes

Allelic Composition	Genetic Background
Nifk^em1(IMPC)Mbp/Nifk^em1(IMPC)Mbp	C57BL/6NCrl-Nifk^em1(IMPC)Mbp/Mmucd