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Phenotype Image Detail
Image
Caption Smarce1em1(IMPC)J/Smarce1em1(IMPC)J mutants are recovered at lower than expected ratios at E3.5, but both male and female mutants are present. At E7.5, out of 56 embryos 3 mutants were recovered, but appeared as Reichert's membrane only. Mutants appear as blastocysts. Mutants hatch from the zona and form outgrowths. RNA-seq data indicates robust maternal and post-8-cell expression. Additional information at websites.umass.edu/jmager/Smarce1
Copyright This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207
Associated
Alleles
Symbol Name
Smarce1em1(IMPC)J SWI/SNF related BAF chromatin remodeling complex subunit E1; endonuclease-mediated mutation 1, Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Smarce1em1(IMPC)J/Smarce1em1(IMPC)J C57BL/6NJ-Smarce1em1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory