Phenotype Image Detail

Image

Caption

Sptb^em1(IMPC)J/Sptb^em1(IMPC)J embryos cannot be recovered at E7.5 (0/30), nor are there excess resorption sites. Homozygous mutants are recovered at E3.5 and appear as dying morula. Mutants fail to hatch from the zona and are dead after 72hr in vitro, never forming outgrowths. RNA-seq data indicates maternal and pre-implantation expression. Additional information at websites.umass.edu/jmager/Sptb

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Sptb^em1(IMPC)J	spectrin beta, erythrocytic; endonuclease-mediated mutation 1, Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Sptb^em1(IMPC)J/Sptb^em1(IMPC)J	C57BL/6NJ-Sptb^em1(IMPC)J/Mmjax