Phenotype Image Detail

Image

Caption

Nup93^em1(IMPC)Mbp/Nup93^em1(IMPC)Mbp embryos cannot be recovered at E7.5 (0/22), however excess resorption sites suggest mutants elicit a decidual response in vivo. Homozygous mutants are recovered at E3.5 and appear as early blastocysts. Mutants hatch from the zona and form irregular outgrowths with no apparent inner cell mass or trophoblast giant cells. RNA-seq data indicates robust post-zygotic expression. Additional information at websites.umass.edu/jmager/Nup93

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Nup93^em1(IMPC)Mbp	nucleoporin 93; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis

Associated Genotypes

Allelic Composition	Genetic Background
Nup93^em1(IMPC)Mbp/Nup93^em1(IMPC)Mbp	C57BL/6NCrl-Nup93^em1(IMPC)Mbp/Mmucd