Phenotype Image Detail

Image

Caption

Polr2b^em1(IMPC)Bay/Polr2b^em1(IMPC)Bay embryos cannot be recovered at E7.5 (0/31), nor are there excess resorption sites. Homozygous mutants are recovered at expected ratios at E3.5 and appear as dying morula. Mutants fail to hatch from the zona and are dead after 72 hr outgrowth culture. RNA-seq data indicates robust maternal and post-zygotic expression. Additional information at websites.umass.edu/jmager/Polr2b

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Polr2b^em1(IMPC)Bay	polymerase (RNA) II (DNA directed) polypeptide B; endonuclease-mediated mutation 1, Baylor College of Medicine

Associated Genotypes

Allelic Composition	Genetic Background
Polr2b^em1(IMPC)Bay/Polr2b^em1(IMPC)Bay	C57BL/6N-Polr2b^em1(IMPC)Bay/Mmmh