Phenotype Image Detail

Image

Caption

Cog1^em1(IMPC)Bay/Cog1^em1(IMPC)Bay embryos cannot be recovered at E7.5 (0/30), however excess resorption sites suggest mutants elicit a decidual response in vivo. Homozygous mutants are recovered at E3.5 and appear as early blastocysts. Mutants hatch from the zona and form irregular outgrowths with poorly defined inner cell mass. RNA-seq data indicates robust maternal and post-2 cell expression. Additional information at websites.umass.edu/jmager/Cog1

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Cog1^em1(IMPC)Bay	component of oligomeric golgi complex 1; endonuclease-mediated mutation 1, Baylor College of Medicine

Associated Genotypes

Allelic Composition	Genetic Background
Cog1^em1(IMPC)Bay/Cog1^em1(IMPC)Bay	C57BL/6N-Cog1^em1(IMPC)Bay/Mmmh