Phenotype Image Detail

Image

Caption

Casc3^{tm1.1(KOMP)Vlcg}/Casc3^{tm1.1(KOMP)Vlcg} mutants are recovered in expected ratios at E7.5 but appear smaller than littermates. Although the primitive streak has formed, no morphological node or other hallmarks typical of E7.5 (i.e. headfolds) are present. Both LacZ reporter and RT-PCR indicate wide-spread expression during gastrulation stages. Additional information at websites.umass.edu/jmager/Casc3

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Casc3^tm1.1(KOMP)Vlcg	exon junction complex subunit; targeted mutation 1.1, Velocigene

Associated Genotypes

Allelic Composition	Genetic Background
Casc3^tm1.1(KOMP)Vlcg/Casc3^tm1.1(KOMP)Vlcg	C57BL/6N-Casc3^tm1.1(KOMP)Vlcg/MbpMmucd