Phenotype Image Detail

Image

Caption

Ddx46^em1(IMPC)Tcp/Ddx46^em1(IMPC)Tcp embryos cannot be recovered at E7.5 (0/22), however excess resorption sites suggest mutants elicit a decidual response in vivo. Homozygous mutants are recovered at E3.5 and appear as blastocysts. Mutants hatch from the zona but form irregular outgrowths. RNA-seq data indicates robust maternal and zygotic expression. Additional information at websites.umass.edu/jmager/Ddx46

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Ddx46^em1(IMPC)Tcp	DEAD box helicase 46; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Associated Genotypes

Allelic Composition	Genetic Background
Ddx46^em1(IMPC)Tcp/Ddx46^em1(IMPC)Tcp	C57BL/6N-Ddx46^em1(IMPC)Tcp/Cmmr