Phenotype Image Detail

Image

Caption

Sec61g^em1(IMPC)J/Sec61g^em1(IMPC)J embryos cannot be recovered at E7.5 (0/30), however excess reabsorption sites suggest mutants elicit a decidual response in vivo. Homozygous mutants can be recovered in expected ratios at E3.5 and appear as early blastocysts. Mutants fail to hatch from the zona and are dead after 72hr in vitro outgrowth culture. RNA-seq data indicates robust expression. Additional information at websites.umass.edu/jmager/sec61g

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Sec61g^em1(IMPC)J	SEC61 translocon subunit gamma; endonuclease-mediated mutation 1, Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Sec61g^em1(IMPC)J/Sec61g^em1(IMPC)J	C57BL/6NJ-Sec61g^em1(IMPC)J/Mmjax