Phenotype Image Detail

Image

Caption

Ddx18^em1(IMPC)Bay/Ddx18^em1(IMPC)Bay embryos cannot be recovered at E7.5 (0/31), nor are there excess reabsorption sites. Homozygous mutants can be recovered at E3.5 and appear as uncompacted morula. Mutants fail to hatch from the zona and are dead after 72hr in vitro outgrowth culture. RNA-seq data indicates robust expression. Additional information at websites.umass.edu/jmager/ddx18

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Ddx18^em1(IMPC)Bay	DEAD box helicase 18; endonuclease-mediated mutation 1, Baylor College of Medicine

Associated Genotypes

Allelic Composition	Genetic Background
Ddx18^em1(IMPC)Bay/Ddx18^em1(IMPC)Bay	C57BL/6NJ-Ddx18^em1(IMPC)Bay/Mmnc