Phenotype Image Detail

Image

Caption

Ruvbl2^em1(IMPC)Bay/Ruvbl2^em1(IMPC)Bay embryos cannot be recovered at E7.5 (0/24), however excess reabsorption sites suggest mutants elicit a decidual response in vivo. Homozygous mutants are recovered at E3.5 and appear as blastocysts. Mutants hatch from the zona and form irregular outgrowths with poorly defined inner cell mass colony when cultured in vitro. RNA-seq data indicates robust maternal and post-2-cell expression. Additional information at websites.umass.edu/jmager/ruvbl2

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
Ruvbl2^em1(IMPC)Bay	RuvB-like AAA ATPase 2; endonuclease-mediated mutation 1, Baylor College of Medicine

Associated Genotypes

Allelic Composition	Genetic Background
Ruvbl2^em1(IMPC)Bay/Ruvbl2^em1(IMPC)Bay	C57BL/6NJ-Ruvbl2^em1(IMPC)Bay/Mmnc