Phenotype Image Detail

Image

Caption

B4gat1^{tm1.1(KOMP)Vlcg}/B4gat1^{tm1.1(KOMP)Vlcg} mutants are recovered in expected ratios at E7.5 but are much smaller than littermates. A rudimentary egg cylinder has formed, but no morphological primitive streak or other hallmarks typical of gastrulation at E7.5 (i.e. node, headfolds) are present. RT-PCR indicates developmentally regulated expression. Knock-in LacZ reporter shows no signal at E6.5, and weak staining at E7.5 and E8.5. Additional information at websites.umass.edu/jmager/B4gat1

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Associated Alleles

Symbol	Name
B4gat1^tm1.1(KOMP)Vlcg	beta-1,4-glucuronyltransferase 1; targeted mutation 1.1, Velocigene

Associated Genotypes

Allelic Composition	Genetic Background
B4gat1^tm1.1(KOMP)Vlcg/B4gat1^tm1.1(KOMP)Vlcg	C57BL/6N-B4gat1^tm1.1(KOMP)Vlcg/MbpMmucd