About   Help   FAQ
Molecular Image Detail
Image
Caption A, targeting strategy. Schematic diagram of the wild-type (WT) Lcn2 (24p3) gene (top), the targeting construct (middle), and the Lcn2tm1Mrgr knock-out (KO) allele (bottom). After homologous recombination, the targeting vector replaces exons 1-5 (indicated by gray boxes) with the phosphoglycerate kinase-neomycin resistance gene (PGK-neo) cassette. The external 5'-flanking probe is indicated, as are the positions of PCR primers for detecting WT (P1 and P2) and mutant KO (P1 and P3) alleles. The position of the external 5'-flanking probe used for Southern blot analysis is indicated, as are the BamHI sites (denoted by the letter B).
Copyright This image is from Liu Z, J Biol Chem 2011 Jun 10;286(23):20606-14 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:173490
Associated
Alleles
Symbol Name
Lcn2tm1Mrgr lipocalin 2; targeted mutation 1, Michael R Green

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory