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Caption (a) Structures of mouse Stk11 gene (exons 1-10), targeting vector, and the predicted structures of targeted Stk11tm1Jish and null Stk11tm1.1Jish alleles, which can be generated from targeted allele by Cre-loxP-mediated recombination. In the targeting vector, the neomycin gene (neor) flanked by two loxP sequences was inserted in the HindIII site at intron 1, and one more loxP sequence was inserted in another HindIII site just after exon 8. Localization of each PCR primer and probes for Southern blots used to detect each allele are indicated. The positions of restriction sites of BamHI (B) and Kpnl (K) are also indicated.
Copyright This image is from Jishage K, Proc Natl Acad Sci U S A 2002 Jun 25;99(13):8903-8. Copyright 2002 National Academy of Sciences, U.S.A. J:77213
Associated
Alleles
Symbol Name
Stk11tm1.1Jish serine/threonine kinase 11; targeted mutation 1.1, Kou-ichi Jishage
Stk11tm1Jish serine/threonine kinase 11; targeted mutation 1, Kou-ichi Jishage

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory