| Image |
|
||||||||
| Caption | (A) Strategy for targeting the Mapk14 (p38alpha) locus. The genomic structure, targeting vector, and targeted allele for Mapk14tm3.1(Mapk11)Nbr (p38betaKIalpha) are shown. The construct consisted of an in-frame-cloned Mapk11 (p38beta) cDNA fused to a SV40 polyA sequence followed by a loxP-flanked neomycin resistance cassette, a 3.3-kb 5' homology arm, and a 7.9-kb 3' homology arm. The A subunit of diphtheria toxin was used as a counter selection marker. Heterozygous mice containing the neomycin resistance cassette (p38beta KI alphaneo/+) mice were intercrossed with the CMV-Cre transgenic line to remove the neomycin resistance cassette. | ||||||||
| Copyright | This image is from del Barco Barrantes I, Proc Natl Acad Sci U S A 2011 Aug 2;108(31):12764-9. Copyright 2011 National Academy of Sciences, U.S.A. J:176023 | ||||||||
|
Associated Alleles |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/12/2024 MGI 6.24 |
|
|
|
||
Analysis Tools