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Molecular Image Detail
Image
Caption (A) Model of the DNA construct used for Muc5ac gene disruption to generate the Muc5actm1.1Evns allele. LoxP sites (yellow flags) were inserted 1173 bp upstream and 265 bp downstream of the Muc5ac translational start site. A neomycin resistance cassette flanked by FRT sites located directly adjacent to the 5' LoxP site was used for positive selection, and the selection cassette was removed by crossing animals with ROSA26-FLPe knockin mice (not depicted).
Copyright This image is from Hasnain SZ, J Exp Med 2011 May 9;208(5):893-900, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:177306
Associated
Alleles
Symbol Name
Muc5actm1.1Evns mucin 5, subtypes A and C, tracheobronchial/gastric; targeted mutation 1.1, Christopher M Evans

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory