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| Caption | (A) Schematic representation of part of the targeting strategy that results in the deletion of Ppp1r13l exon 8 and generates the Ppp1r13ltm1.1Xlu allele. The primers used to confirm exon 8 deletion are shown (red arrows). Black box represents Ppp1r13l exon 8, whereas blue triangles represent loxP sites (left). The presence or absence of Ppp1r13l exon 8 was confirmed by PCR analysis using specific primers. The deleted allele was generated after Cre-mediated recombination of two loxP sites, resulting in a 800-bp PCR product detected using Ppp1r13l-specific primers I8-2 and FLP2 and produced a 600bp PCR band. The detection of the wild-type allele was carried out using Ppp1r13l-specific primers I8-2 and E8-2. The detection of both bands indicates heterozygous mice (right). | ||||
| Copyright | This image is from Notari M, Proc Natl Acad Sci U S A 2011 Oct 4;108(40):16645-50. Copyright 2011 National Academy of Sciences, U.S.A. J:177360 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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