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| Caption | (A) The targeting vector (middle) to generate the Snap25tm1Mtaka allele, was constructed by insertion of the DNA fragment (lower), consisting of part of a mutated SNAP-25 minigene, the PGK 3' end poly-A signal, the PGK promoter and the neo gene, into the SmaI site at exon 7 of the region between exon 6 and exon 8 of the wild-type allele (upper). The black box in the lower panel indicates the mutation point of the codon for Ser187 to Ala187. Arrows indicate the primers used in ES cell screening. | ||||
| Copyright | This image is from Kataoka M, PLoS One 2011;6(9):e25158, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:177870 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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