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Caption | (A) Schematic diagram of wild-type and mutant Atad5 loci to generate the Atad5Gt(RRF055)Byg allele. Exons 17-19 are indicated as solid boxes. LacZ and NEO indicate the location of the cassette that disrupted Atad5 gene expression by insertional mutagenesis. Arrows and numbers between arrows indicate the locations of primers used for genotyping and expected sizes of PCR products, respectively. PCR with gray and black primer that can bind wild-type locus generates 542 bp PCR products from wild type loci but not in mutant locus due to the inserted LacZ-NEO cassette. In contrast, PCR with gray and another black primer that can bind LacZ sequence generates 900 bp PCR product only from mutant locus. | ||||
Copyright | This image is from Bell DW, PLoS Genet 2011 Aug;7(8):e1002245, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:176672 | ||||
Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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