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Molecular Image Detail
Image
Caption (A) Schematic diagram of wild-type and mutant Atad5 loci to generate the Atad5Gt(RRF055)Byg allele. Exons 17-19 are indicated as solid boxes. LacZ and NEO indicate the location of the cassette that disrupted Atad5 gene expression by insertional mutagenesis. Arrows and numbers between arrows indicate the locations of primers used for genotyping and expected sizes of PCR products, respectively. PCR with gray and black primer that can bind wild-type locus generates 542 bp PCR products from wild type loci but not in mutant locus due to the inserted LacZ-NEO cassette. In contrast, PCR with gray and another black primer that can bind LacZ sequence generates 900 bp PCR product only from mutant locus.
Copyright This image is from Bell DW, PLoS Genet 2011 Aug;7(8):e1002245, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:176672
Associated
Alleles
Symbol Name
Atad5Gt(RRF055)Byg ATPase family, AAA domain containing 5; gene trap RRF055, BayGenomics

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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory