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| Caption | A, diagram from the top to the bottom shows: wild type Tnni3, the exon-intron organization and simplified restriction map of the murine Tnni3 gene; targeting vector, the targeted construct region to introduce the loxP flanked neo cassette, tk gene, and the R21C mutation; mutated Tnni3 (Tnni3tm1Jdp), the mutated Tnni3 gene after homologous recombination and the probes used for Southern blotting to identify the targeted ES cell clone and the mutated mice; neo deleted, the R21C mutation in the targeted Tnni3 gene after neo deletion to generate the Tnni3tm1.1Jdp allele. Restriction sites: C, ClaI; H, HindIII; Rv, EcoRV; S, Sac1; Sal, SalI; Sm, SmaI; Xh, XhoI. | ||||||
| Copyright | This image is from Wang Y, J Biol Chem 2012 Jan 13;287(3):2156-67 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:180606 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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