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| Caption | Schematic representation of the Pmel+, Pmeltm1Sson (PmelloxP), and Pmeltm1.1Sson (Pmel-) alleles. The exons (gray boxes), primers used for genotyping (black arrowheads), KpnI restriction cleavage sites and the target site of Southern blot probe (SP, black box) are all indicated. In the Pmeltm1Sson allele, exon 2 and exon 3 are loxP-flanked (red circles) and a neomycin (green box) gene is flanked by two FRT-sites (blue boxes). In the Pmeltm1.1Sson allele, exon 2 and exon 3 are deleted after Cre-recombinase induced homologous recombination between the loxP sites. | ||||||
| Copyright | This image is from Hellstrom AR, PLoS Genet 2011 Sep;7(9):e1002285, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:177116 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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