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| Caption | Generation of the Pclaftm1.1Lkd allele. (B) Partial genomic structure of the RIKEN cDNA 2810417H13 (Paf) mouse gene and Trip4 gene, which is embedded in the 2810417H13 locus. Black and red rectangles represent the 2810417H13 and Trip4 gene exons, respectively. The black box represents the Diphtheria toxin-ampicillin negative selection cassette and the gray box represents the Neomycin positive selection cassette flanked by FRT recombination sites (purple crescents), inserted into the 5'-UTR region of exon 1. Triangles (green) show the loxP sites. The arrow represents the translation start site. Light blue lines flanked with arrows show the fragments and sizes of the fragments generated upon NcoI (N) digestion of genomic DNA in the targeted and nontargeted locus and light blue vertical lines denote the NcoI restriction site. Box A (orange) shows the probe that was used for screening of NcoI digested genomic DNA. | ||||
| Copyright | This image is from Amrani YM, J Exp Med 2011 Aug 29;208(9):1757-65, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:177782 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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