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| Caption | (A) Targeting strategy for the mouse Fgf23tm1.1Kew (Fgf23-R176Q LoxP-Neor) allele. This mutation was introduced (triangle) into exon 3 of the mouse Fgf23 gene. A floxed-neomycin resistance gene (Neor) cassette was placed into intron 2, and a silent SacI site was introduced into exon three, 3' to the R176Q mutation. (B) The LoxP-Neor cassette in the Fgf23-R176Q LoxP-Neo allele was removed by breeding to an EIIa-Cre transgenic mouse and generated the Fgf23tm1.1Kew allele. | ||||
| Copyright | This image is from Farrow EG, Proc Natl Acad Sci U S A 2011 Nov 15;108(46):E1146-55. Copyright 2011 National Academy of Sciences, U.S.A. J:180061 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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