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| Caption | C) The third exon of CARM1 (*) harbors a critical arginine residue (Arg169) that was mutated to an alanine in the original knock-out construct to generate a knock-in construct. Heterozygous mice were crossed with a Flp recombinase-expressing mouse to remove the Neo cassette and generate the Carm1tm2.1Mtb allele. Arrowheads depict loxP sites; solid boxes depict exons; and gray boxes depict frt sites. The position of the external Southern probe is noted. | ||||
| Copyright | This image is from Kim D, J Biol Chem 2010 Jan 8;285(2):1147-52 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:159958 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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