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| Caption | A, first row, sequence around the IQ motif of CACNA1C. Second row, genomic DNA structure of CACNA1C. Boxes represent exons 39-44 encoding part of the C terminus of Cacna1c. Third row, targeting vector, neo, neomycin resistance gene; tk, thymidine kinase gene with loxP sequence (triangles) at both sides. The I1624E substitution is shown. Fourth row, the knock-in locus after homologous recombination and Cre-mediated deletion of resistance markers generating the Cacna1ctm4Hfm allele. N, NotI; B, BamHI; C, ClaI; X, XhoI; E, EcoRI; H, HindIII. | ||||
| Copyright | This image is from Poomvanicha M, J Biol Chem 2011 Jul 29;286(30):26702-7 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:175463 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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