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| Caption | Targeted modification of the Capns1 gene to generate the floxed Capns1tm1.1Otsu allele and the resulting conditional mutant upon removal of the floxed region. A, schematic structures of genomic Capns1 sequences, the targeting construct, the targeted allele, the type II deletion, and the conditional knock-out allele (from top to bottom). The arrowheads represent loxP sites. The targeting construct includes the PGK-neo cassette flanked by loxP sites and a diphtheria toxin gene (DTA). The arrows correspond to the primer sequences for PCR screening. | ||||
| Copyright | This image is from Taneike M, J Biol Chem 2011 Sep 16;286(37):32170-7 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:176736 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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