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| Caption | Targeting of the Rgs7 gene to generate the Rgs7tm1Cjch allele. A, partial map of the mouse Rgs7 gene, targeted exons, and the targeting construct containing negative and positive selection markers in DTA and NEO, respectively. Upon homologous recombination to generate the Rgs7tm1Cjch allele, exons 6-8 are replaced with the NEO marker, whereas the DTA markers are concurrently lost. Restriction enzyme sites in parentheses are present in the backbone pDND7-F vector and were introduced by PCR during the amplification of homology arms. | ||||
| Copyright | This image is from Shim H, J Biol Chem 2012 Apr 27;287(18):14873-9 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:184922 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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