Molecular Image Detail

Image

Caption

Targeting strategy for introducing point mutations in the cytoplasmic domain of Itgb1 (beta1A integrin). (A) Partial map of the Itgb1 wild-type (wt) gene, the KI allele with a point mutation (indicated by asterisk) in exon 16 (E16) before (KI^neo+) and after (KI^lox) Cre-mediated deletion of the floxed neo cassette, generating either the Itgb1^tm9.1Ref, Itgb1^tm10.1Ref, Itgb1^tm11.1Ref, or Itgb1^tm12.1Ref allele. Filled boxes indicate exons, and triangles indicate loxP sites.

This image is from Czuchra A, J Cell Biol 2006 Sep 11;174(6):889-99, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:177979

Associated
Alleles

Symbol	Name
Itgb1^tm10.1Ref	integrin beta 1 (fibronectin receptor beta); targeted mutation 10.1, Reinhard Fassler
Itgb1^tm11.1Ref	integrin beta 1 (fibronectin receptor beta); targeted mutation 11.1, Reinhard Fassler
Itgb1^tm12.1Ref	integrin beta 1 (fibronectin receptor beta); targeted mutation 12.1, Reinhard Fassler
Itgb1^tm9.1Ref	integrin beta 1 (fibronectin receptor beta); targeted mutation 9.1, Reinhard Fassler

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