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Molecular Image Detail
Image
Caption A) The Pmchtm1.1(HBEGF)Rpa allele (right, PmchDTR) expresses the human DT receptor (hDTR) from the Pmch promoter, followed by an internal ribosome entry site (ires) and EGFP. These transgenes replace parts of the first and second exons of the wild-type Pmch allele (left) between the initiation codon, ATG, and a BamH1 site.
Copyright This image is from Wu Q, Proc Natl Acad Sci U S A 2012 Feb 21;109(8):3155-60. Copyright 2012 National Academy of Sciences, U.S.A. J:181947
Associated
Alleles
Symbol Name
Pmchtm1.1(HBEGF)Rpa pro-melanin-concentrating hormone; targeted mutation 1.1, Richard D Palmiter

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory