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| Caption | A, schematic illustration of the exon organization of the Ep400 (p400/mDomino) gene and targeting strategy. A targeting vector was designed in which exon 15 was flanked by two loxP sites, and an FRT/loxP-flanked Neo cassette (NeoFRT) was inserted into intron 15. Removal of the NeoFRT cassette by FLPe recombinase generated the Ep400tm3Fuku (mDomfl) allele. Cre-mediated recombination between the loxP sites generated the exon-15-deleted allele, Ep400tm3.1Fuku (mDomdelta). The positions of the primers used for genotyping are indicated by short arrows. | ||||||
| Copyright | This image is from Fujii T, J Biol Chem 2010 Sep 24;285(39):30214-23 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166397 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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