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Caption Generation of the floxed Aiptm2.1Bra allele. A, genome maps of native mouse Aip gene (Aip+), hypomorphic Aip allele (Aipfxneo), conditional Aip allele Aiptm2.1Bra (Aipfx), and hepatocyte Aip null allele (AipfxCrealb). Mice carrying the floxed Aiptm2.1Bra allele can be mated with Cre recombinase expressing mice to delete exons 3-6 conditionally, as shown here. Open boxes, exon 2 to exon 6 of mouse Aip gene; Neo, neomycin resistance cassette; white arrowheads, Lox-P sites; black arrowheads, Frt sites; OL, PCR primers.
Copyright This image is from Nukaya M, J Biol Chem 2010 Nov 12;285(46):35599-605 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166864
Associated
Alleles
Symbol Name
Aiptm2.1Bra aryl-hydrocarbon receptor-interacting protein; targeted mutation 2.1, Christopher A Bradfield

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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory