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| Caption | Targeted mutation of Spdef to generate the Spdeftm1Shiv allele. A, the targeting vector carried a 5-kb EcoRI/HindIII fragment as the left homology arm and a 2.6-kb HindIII/BglII fragment as the right arm, flanking a NeoR cassette. In the targeted allele, 5.1 kb of Spdef sequence spanning exons 2-5 was replaced with the PGK-NeoR cassette. tk, thymidine kinase. | ||||
| Copyright | This image is from Horst D, J Biol Chem 2010 Nov 5;285(45):35047-55 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166876 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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