Molecular Image Detail

Image

Caption

(A) "Porcn locus" represents the wild-type (WT) locus; "Targeted Allele" contains loxP sites in introns 2 and 7 and an FRT-flanked neomycin (Neo) gene in intron 7 (Porcn-ex3-7-Neo-flox), generating the Porcn^tm1Vdv allele; "Floxed Allele" retains only loxP sites after excision of Neo (Porcn-ex3-7flox) and generates the Porcn^tm1.1Vdv allele; "Deleted Allele" lacks exons 3 through 7 (Porcn-ex3-7del) and gives rise to the Porcn^tm1.2Vdv allele. P1-P4 indicate the location of the various genotyping primers; blue boxes represent the probes for sourthern analysis; E = EcoRI and S = ScaI restriction sites; sizes for diagnostic fragments for southern analysis are also shown.

This image is from Liu W, PLoS One 2012;7(3):e32331, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:186934

Associated
Alleles

Symbol	Name
Porcn^tm1.1Vdv	porcupine O-acyltransferase; targeted mutation 1.1, Ignatia B Van den Veyver
Porcn^tm1.2Vdv	porcupine O-acyltransferase; targeted mutation 1, Ignatia B Van den Veyver
Porcn^tm1Vdv	porcupine O-acyltransferase; targeted mutation 1, Ignatia B Van den Veyver

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